To restart or not to restart – that is the question. My rheumatologist has prescribed me methotrexate again. She stated again at my last appointment that studies prove that the biologic medications work better when they are taken with methotrexate. Which may be true, but I remember vividly the reasons as to why I told my rheumatologist in Darwin that I would be discontinuing methotrexate in January 2007.
After 15 years of weekly doses of methotrexate (orally to begin with before eventually progressing to injections), the nausea, fatigue and generally feeling unwell took it’s toll and I craved a feeling of normality.
I’ve been off methotrexate now for 7 years and I am seriously considering beginning treatment again. i tell all my medical team that the best biologic I had ever been on was Etanercept and that nothing had worked as well since. In hindsight I also have taken methotrexate with any of the other biologics so it possibly isn’t a fair assumption that the other medications didn’t work as well. Taken properly (in conjunction with other medications as prescribed), they may well have been just as good.
Writing about this tonight has helped me make the decision to give methotrexate another try. I was on 30mg per week before I ceased treatment so maybe asking my rheumatologist to prescribe a smaller dose of 10mg per week to start with and increase from there if necessary might be a better way to go. The last thing I want with having two small children, work and trying to set up a business is to spend the vast majority of my day feeling sick.
See how we go…